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Wei Dou Selected Research

Pregnane X Receptor

1/2021Deciphering structural bases of intestinal and hepatic selectivity in targeting pregnane X receptor with indole-based microbial mimics.
11/2019Activation of PXR by alantolactone ameliorates DSS-induced experimental colitis via suppressing NF-κB signaling pathway.
2/2015Notoginsenoside R1 attenuates experimental inflammatory bowel disease via pregnane X receptor activation.
9/2014Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.
11/2013Reverse yeast two-hybrid system to identify mammalian nuclear receptor residues that interact with ligands and/or antagonists.
6/2013Chrysin ameliorates chemically induced colitis in the mouse through modulation of a PXR/NF-κB signaling pathway.
1/2012Alleviation of gut inflammation by Cdx2/Pxr pathway in a mouse model of chemical colitis.

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Wei Dou Research Topics

Disease

16Inflammation (Inflammations)
03/2024 - 01/2012
15Neoplasms (Cancer)
04/2024 - 05/2010
14Colitis
04/2024 - 06/2013
8Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2020 - 06/2013
7Diarrhea
04/2024 - 11/2014
7Infections
05/2023 - 10/2008
6Body Weight (Weight, Body)
09/2023 - 03/2012
4Ulcerative Colitis
01/2020 - 09/2014
3Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 12/2020
2Adenocarcinoma
04/2024 - 11/2014
2Hyperplasia
04/2024 - 02/2014
2Colonic Neoplasms (Colon Cancer)
12/2021 - 01/2014
2Crohn Disease (Crohn's Disease)
11/2017 - 09/2014
2Psoriasis (Pustulosis Palmaris et Plantaris)
01/2015 - 02/2014
2Metabolic Syndrome (Dysmetabolic Syndrome X)
09/2010 - 02/2008
1Adenoma (Adenomas)
04/2024
1Weight Loss (Weight Reduction)
04/2024
1Carcinogenesis
04/2024
1Experimental Arthritis
04/2024
1Arthritis (Polyarthritis)
04/2024
1Alopecia (Baldness)
10/2023
1Pain (Aches)
08/2023
1Hematologic Neoplasms (Hematological Malignancy)
01/2021
1Vomiting
01/2021
1Mucositis
01/2021
1Nausea
01/2021
1Splenomegaly
12/2020
1Dengue (Dengue Fever)
10/2019
1Headache (Headaches)
06/2018
1Allergic Rhinitis
06/2018
1Sinusitis
06/2018
1Acquired Immunodeficiency Syndrome (AIDS)
01/2018

Drug/Important Bio-Agent (IBA)

9Dextran SulfateIBA
01/2020 - 01/2014
7Pregnane X ReceptorIBA
01/2021 - 01/2012
7Peroxidase (Myeloperoxidase)IBA
06/2018 - 01/2014
6CytokinesIBA
04/2024 - 02/2014
6Messenger RNA (mRNA)IBA
12/2020 - 09/2010
4FlavonoidsIBA
01/2020 - 01/2012
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2018 - 06/2013
4Interleukin-6 (Interleukin 6)IBA
10/2015 - 06/2013
3Irinotecan (Camptosar)FDA LinkGeneric
04/2024 - 01/2021
3Proteins (Proteins, Gene)FDA Link
12/2021 - 01/2020
3Toll-Like Receptor 4IBA
01/2020 - 08/2013
3Sulfonic AcidsIBA
11/2017 - 06/2013
3Dextrans (Dextran)FDA Link
08/2013 - 01/2012
2Bromodeoxyuridine (BrdU)IBA
04/2024 - 03/2024
2notoginsenoside R1IBA
03/2024 - 02/2015
2InsecticidesIBA
09/2023 - 01/2018
2LipidsIBA
01/2022 - 06/2011
2alantolactoneIBA
12/2021 - 11/2019
2GlucuronidaseIBA
01/2021 - 01/2012
2EnzymesIBA
01/2021 - 01/2018
2obacunoneIBA
12/2020 - 01/2020
2Nitric Oxide (Nitrogen Monoxide)FDA Link
06/2018 - 10/2015
2Antimicrobial PeptidesIBA
01/2018 - 04/2017
2Peptidoglycan (Murein)IBA
01/2018 - 04/2017
2baicaleinIBA
11/2017 - 01/2012
2Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
08/2013 - 06/2013
2Nitric Oxide Synthase (NO Synthase)IBA
08/2013 - 06/2013
2Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
08/2013 - 06/2013
2sodium sulfate (sodium bisulfate)FDA LinkGeneric
06/2013 - 01/2012
211-beta-Hydroxysteroid Dehydrogenase Type 1IBA
09/2010 - 02/2008
1gastrodinIBA
04/2024
1Antineoplastic Agents (Antineoplastics)IBA
04/2024
1AlkaloidsIBA
04/2024
1CollagenIBA
04/2024
1nuciferineIBA
04/2024
1ICG 001IBA
03/2024
1SaponinsIBA
03/2024
1RNA (Ribonucleic Acid)IBA
03/2024
1CateninsIBA
03/2024
1Tight Junction ProteinsIBA
03/2024
1Testosterone (Sustanon)FDA Link
10/2023
1Indicators and Reagents (Reagents)IBA
10/2023
1dinotefuranIBA
09/2023
1ChitosanIBA
08/2023
1ribonuclease T(2)IBA
05/2023
1Peptide Hydrolases (Proteases)FDA Link
01/2023
1Tryptophan (L-Tryptophan)FDA Link
01/2021
1Epithelial Cell Adhesion MoleculeIBA
01/2021
1AntigensIBA
01/2021
1Chimeric Antigen ReceptorsIBA
01/2021
1BerberineIBA
01/2021
1IndolesIBA
01/2021
1MicroRNAs (MicroRNA)IBA
12/2020
1NF-kappa B (NF-kB)IBA
01/2020
1alpinetinIBA
01/2020
1pinocembrinIBA
01/2020
1acacetinIBA
01/2020
1Protein Sorting Signals (Signal Peptide)IBA
01/2020
1juvenile hormone IIIIBA
10/2019
1LignansIBA
06/2018
1fargesinIBA
06/2018
1NADPH-Ferrihemoprotein Reductase (Cytochrome P450 Reductase)IBA
01/2018
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
01/2018
1sym-trinitrobenzeneIBA
11/2017

Therapy/Procedure

4Therapeutics
01/2022 - 01/2012
3Oral Administration
01/2020 - 09/2010
1Photothermal Therapy
01/2022
1Cardiopulmonary Resuscitation (CPR)
01/2018